Alteration of certain pharmacological effects of histamine by selected histaminase inhibitors
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Book Reviews W. Schmutzler : Studien über die Histaminase-Freisetzung beim Meerschweinchen im anaphylaktischen Schock und durch Histaminase-Liberatoren. Freiburg im Br. (Germany) 1966. 109pp. (In German with summary in English). The Archives have had the good fortune to publish a number of original papers from the Pharmacological Institute of the University of Freiburg im Br. during the last fe...
متن کاملخالص سازی و بررسی خواص سینتیکی آنزیم هیستامیناز از گونه خلر ( Lathyrus sativus ) با استفاده از کروماتوگرافی تعویض آنیون
Background : The histamine poisoning directly correlates to improper preservation of foods. Diamine oxidase catalyses the oxidative deamination of histamine and other biogenic amines such as cadaverine and putrescine. Plant diamine oxidases are of widespread occurrence in Leguminaceae such as Cicer arietinum, Lathyrus sativus and Vigna radiata. For this reason, this study was carried out to exa...
متن کامل[Current Medical Practice (1988): (5), 115]
Eighteen male rabbits were used in this trial, divided into three groups of 6 each. Group A served as controls. Group B were on a placebo and received isoprenaline injections. Group C were treated with Abana and also received isoprenaline. Histamine was measured in all the three groups. A significant increase in histamine levels was observed in the isoprenaline group. Two weeks of Abana therapy...
متن کاملHistaminase release from human granulocytes
Histaminase (EC-1.4.3.6), one of the two catabolic enzymes for histamine, is contained in human granulocytes. Opsonized zymosan or the calcium ionophore A-23187 induce a dose-dependent release of histaminase from human granulocytes in vitro. Release is completed within 30 min, is temperature dependent, and requires divalent cations. Opsonized zymosan-induced histaminase release was maximal in t...
متن کاملThe purification and properties of placental histaminase.
1. Histaminase was extracted from desanguinated human placentae and purified by salt fractionation, ion-exchange chromatography and gel filtration. The purest preparation was still contaminated with haptoglobin-methaemoglobin. 2. Histaminase activity was measured by the o-aminobenzaldehyde method of Holmstedt & Tham (1959), Kapeller-Adler's (1951) test and a modified spectrophotometric indigodi...
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